: +1-617-803-9415
As an integrated service to our recognized capabilities and expertise in in vivo pharmacology, Pharmalegacy offers a full span histology, cytology and histopathology services to provide an advanced support for drug discovery in the areas of toxicology, oncology, immuno-oncology, disease of inflammation, metabolic, cardiovascular and neurodegeneration. We routinely perform tissue/cell processing, embedding, sectioning, special histology staining, immuno-histo and –cytochemistry staining as well as in situ hybridization with our cutting-age technology. Our qualified and experienced pathology team member works closely with our clients to assure the highest quality in a timely manner.
· small and large animal necropsy
· high resolution gross necropsy photography
· in-situ perfusion fixation
· ex-vivo organ perfusion fixation
· tissue micro-dissection
· H&E stainingn
· special staining: Masson trichrome,Sirius red, Oil red O, PAS, Silver and others upon request
· immunohistochemical staining (IHC)
· immunofluorescent staining (IF)
· immunocytochemical staining (ICC)
· in situ hybridization (ISH)
· fluorescent in situ hybridization (FISH)
· biomarker screen, location, density on cell lines, tissue microarray, cell line microarray and ex-vivo tissue culture
· non-GLP toxic pathology including gross pathology and histopathology reading, analysis, evaluation, review and report
· biomarker localization, screening via IHC, FISH, ISH on TMA, CMA, human tissue bank, animal tissue bank as well as NHP tissue bank
· gross necropsy photography station
· light microscopes with digital photography
· organ perfusion tanks
· tissue processor
· paraffin microtomes
· cryostat
· tissue slicer
· microscopes with digital photography
· -80 C degree tissue sample storage
· liquid nitrogen tissue sample storage
· regular paraffin embedded block sample storage
· biosafety hood
