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DMPK Services

发布时间 2018-03-05
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DMPK Services


PharmaLegacy Models and Research Tools



PharmaLegacy can provide a complete complementary PK/ADME service. Our team of DMPK scientists are dedicated to both discovery and development. This coupled with state-of-the-art instrumentation and supported by an AAALAC accredited vivarium, assists our clients from lead candidate selection through development and ensures a high quality of DMPK studies with cost-efficiency and fast turnaround.

DMPK Services



Case Study 1 - PK Profiling in Rodent, Non-human Primate and Canine



PK profiling of ANA-088 in SD rats (n=5, A), cynomolgus monkeys (n=3, B) and beagle dogs (n=3, C) after a single dose

DMPK Services



Case Study 2 - PK-PD Study in Hamster



PK-PD study of ANA-077 on high cholesterol diet-induced hyperlipidemia in hamsters

DMPK Services


Note:

All values in PD: Mean +/- SEM; HCD, high cholesterol diet; TC, total cholesterol; TG: triglyceride; HDL-c, HDL-bound cholesterol.





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