案例 Products
产品名称

Human Cancer Cell Selection Panel

发布时间 2018-01-31
点击次数 69
  • 基本参数
  • 部件材质
  • 应用概述
  • 相关下载

Human Cancer Cell Selection Panel


Application:


Human cancer cell selection panel serves for anti-cancer drug discovery. To evaluate the potential cytotoxicity and growth-inhibition effects of the test articles against multi-type tumors in a quick and efficient way. More than 60 human cancer cells can be screened by cell proliferation/cytotoxicity assay, covering Liver, Lung, Breast, Lymphoma, Colon, Melanoma, Leukemia, Myeloma tumors. After the in vitro screen, the most sensitive cancer cell lines can be selected for further tested in xenograft or orthotopic tumor models in mice or rats.

Scopes:

•Screen human cancer cells to find the target cancer cell lines for the test articles

•IC50s

•Compare the anti-cancer potency of a group of test articles

•Evaluate the combination anti-cancer effect of two different test articles

•Custom cancer cell lines


Methods:

•CCK8 assay in suspension cells, and MTT or SRB assay in adhesion cells

•96-well plate assays. Each test article will be tested in 6 concentrations, and each concentration will be tested in triplicates

•The assay will be independently repeated once


Human Cancer Cell Selection Panel


Further in Vivo Study:


Tumor cell lines can be further tested in s.c. xenograft models in mice or rats. Some of the cell lines have also been validated in orthotopic and metastatic models.

Tumor Type

No.

Cell Line


Tumor Type

No.

Cell Line

 

Brain

1

U-87 MG

 

Lymphoma

39

Daudi

2

IMR-32

40

RL

Cecum

3

NCI-H716

41

CA46

 

Cervix

4

Ca Ski

 

 

 

Mammary gland

42

MDA-MB-231

5

HeLa

43

MDA-MB-435s

 

 

Colon

6

HCT 116

44

MCF7

7

HT-29

45

BT-20

8

COLO 205

46

SK-BR-3

9

HCT-15

47

BT-474

Endometrium

10

HEC-1-B

 

Melanoma

48

A-375

Epidermoid Carcinoma

11

A431

49

HT-144

Fibrosarcoma

12

HT-1080

50

G-361

 

Gastric

13

NCI-N87

 

Myeloma

51

RPMI 8226

14

AGS

52

U266B1

15

MKN-45

53

ARH77

Kidney

16

A-704

Ovary

54

SK-OV-3

 

 

Leukemia

17

MV-4-11

 

Pancreas

55

BxPC-3

18

HL-60

56

PANC-1

19

K-562

Pharynx

57

FaDu

20

KU812

 

Prostate

58

PC-3

Liposarcoma

21

SW872

59

DU 145

 

 

 

 

 

Liver

22

Hep G2

60

22RV1

23

SK-HEP-1

Rectum

61

SW837

24

HEP 3B

Rhabdomyosarcoma

62

SJCRH30

25

SMMC-7721

 

Osteosarcoma,bone

63

MG-63

26

BEL-7402

64

143B

27

Huh7

T lymphoblast

65

MOLT-4

28

HCC-LM3

Urinary bladder

66

5637

29

MHCC97L

 

 

 

 

 

More cell lines are available upon request.

30

MHCC97H

 

 

 

 

 

Lung

31

NCI-H460

32

A549

33

NCI-H526

34

SK-LU-1

35

DMS 79

36

HCC827

37

NCI-H1975

38

NCI-H446

 


 


Products / 相关产品
2018 - 03 - 05
Immuno-Oncology IntroductionImmuno-therapy has now been representing a significant paradigm shift in cancer treatment after the promising clinical data from the immune-checkpoint m...
2018 - 03 - 02
Gastric Carcinoma     Introduction     Gastric carcinoma remains a common disease with a dismal prognosis. It represents the fourth most frequent mali...
2018 - 03 - 02
With 655,000 deaths worldwide per year, colorectal cancer (CRC) is the second leading cause of cancer-related death in Western society and the incidence and mortality are increasing dramatically in th...
Copyright ©2013 - 2018 
澎立生物医药技术(上海)有限公司
犀牛云提供企业云服务
X
1

QQ设置

3

SKYPE 设置

4

阿里旺旺设置

5

电话号码管理

  • +86-21-6100-2270
6

二维码管理

等待加载动态数据...

等待加载动态数据...

回到顶部
展开