--- title: "All Models" canonical: "https://www.pharmalegacy.com/all-models/" lastmod: "2023-06-27T20:52:22+00:00" generator: "llm-mirrors/1.0.19" --- All Our Models Search All Models Non-Human Primates Capabilities DMPK Ophthalmic Diseases Models Ophthalmic Drug Administration Ophthalmic Examination In Vitro Platform Oncology / Immuno-oncology Platform Inflammation & Autoimmune Diseases Platform Bone / Orthopedics Hearing Impairment Models Histopathology Pain Models Medical Devices Non-Human Primates Capabilities Hematology / Thrombosis Models Arteriovenous Bypass (AV-shunt) Thrombosis Model Balloon Injury-Induced Arterial Thrombosis Bleeding Time Test in Rat Tail or Rabbit Ear / Nail or Arm-skin of Cynos Collagen / FⅧ Induced Hemophilia FeCl3 Induced Thrombosis Model Heart Failure Model Hemorrhagic Stroke Model Immune Thrombocytopenia (ITP) Model Induced by an Anti-GPIIb/IIIa Antibody IVC Stenosis Model of Venous Thrombosis Middle Cerebral Artery Occlusion (MCAO) Induced Stroke Model Myocardial Infarction Myocardial Ischemia / Reperfusion Injury in Rat Venous Bypass Thrombosis Model (V-shunt) In Vitro Testing Services Blood Cell Culture Stimulation Experiment In Vitro Coagulation Measurement In Vitro Determination of Dose-effect of Anticoagulants In Vitro Measurement of Platelet Aggregation Inflammation / Immune Disease Models Acute Hepatitis Induced by Acetaminophen Asthma-like Th2 Response Induced by Multiple A.Suum Challenges in Monkey B-cell Depletion Therapy Balloon Synovitis of the Back Bile Duct Ligation Induced Hepatic Fibrosis Bleomycin-induced Pulmonary Fibrosis Chemotherapy Induced Mucositis Model Collagen II-induced Rheumatoid Arthritis (RA) Model Dextran Sulfate Sodium (DSS)-induced Colitis Model Endometriosis Model Induced by Ectopic Implantation Escherichia Coli Induced Skin Blister I.V Low Dose of Lipopolysaccharide (LPS)-induced Cytokines Production Model Induced Atopic Dermatitis Inflammatory Anemia Model Intrabronchial LPS-induced Acute Lung Injury (ALI) Model Keyhole Limpet Hemocyanin (KLH)-induced T cell Dependent Antibody Response (TDAR) Model LPS-induced Systemic Inflammation Model MOG Induced EAE Tetanus Toxoid (TTx)-induced Delayed Type Hypersensitivity (DTH) Model Metabolic Diseases Models Animal Model of Hyperuricemia Gastric Peristalsis Model Functional Dyspepsia Hyperlipidemia Model Intravenous Glucose Tolerance Test (IVGTT) / Oral Glucose Tolerance Test (OGTT) Model Ophthalmology Models Antibody Drug Conjugate (ADC) Induced Corneal Toxicity Efficiency and Efficacy Evaluation of Ocular Gene Therapy Laser-induced Choroidal Neovascularization (CNV) Model Other NHP Models & Studies Blood Cell Apheresis Cutaneous Wound Healing and Scarring Plantar Pain Caused by Dorsal Root Nerve Ligation PK, PD-Tox Anti-Drug Antibody Test (ADA) Non-GLP Toxicology Experiment Pharmacokinetic Analysis Test PK-APTT Steady-state Dose Exploration Test DMPK Bioanalysis Bioanalysis for Large Molecules (Proteins, Antibodies, ADC, Peptides, ADA) Bioanalysis for Small Molecules Candidate Screening / IND Package In Vitro Absorption, Distribution, Metabolism & Excretion Metabolism Identification (Liver Microsomes / Hepatocytes / S9 / In Vivo) Metabolite Stability (Liver Microsomes / Hepatocytes / Plasma) P450 Enzyme (Inhibition / Phenotyping / Induction / TDI) Permeability (Caco-2, MDCK-MDR1-II / PUMPA) Plasma Protein Binding Red Blood Cell / Plasma Partition Ratio Pharmacokinetic (PK) Studies in Rodents, Rabbits, Canines, Pigs & Non-Human Primates Bioavailability & Bioequivalence Blood Brain Barrier Drug Distribution in Tissues Mass Balance (Excretion of Feces, Urine & Bile) PK Profile & PK Parameters Toxicology (Non-GLP) in Rodents, Rabbits, Canines, Pigs & Non-Human Primates Clinical Pathology / Histopathology Repeat Dose Toxicology (DRF, NOAEL) Single Dose Toxicology (MTD, LD50) Topical Toxicity & Systemic Toxicity Toxicokinetics Ophthalmic Diseases Models Cataract Cataract Model in Rats DR / DME CA-I Induced Retinal Edema Oxygen-Induced Retinopathy (OIR) STZ Induced Diabetic Retinopathy Dry AMD Blue Light / Bright Light-induced Retinopathy MNU-induced Retinal Degeneration Oxidative Stress Induced Geographic Atrophy Sodium Iodate Induced RPE / Retinal Degeneration Gene Therapy CAG-LSL-ZsGreen Mice Colony Management and Phenotyping Functional Assessment Glaucoma Acute Intraocular Hypertension Chronic Intraocular Hypertension NMDA Induced RGC Damage Optic Nerve Clamping-induced RGC Damage Ocular Inflammation Allergic Conjunctivitis Conjunctivitis Induced by Staphylococcal Infection Graves’ Orbitopathy IRBP-induced EAU in Mouse / Rat LPS-induced EIU OVA-induced EAC Ocular Surface Disease Benzalkonium Induced Corneal Epithelial Damage Corneal Neovascularization Induced by Stitching / NaOH Burn (Rabbit) Ocular Pain Test Scopolamine + Low Humidity Induced Dry Eye (Mouse) Other Retinal Diseases Inherited Retinal Disease Models Proliferative Vitreoretinopathy (PVR) in Rabbits Retinal Vein Occlusion (RVO) in Rats Two-Stage Laser-induced Subretinal Fibrosis Refractive Myopia Presbyopia Wet AMD Choroid Sprouting Assay DL-AAA-induced Retinal Neovascularization and Leakage HUVEC Tube Formation Assay Laser-induced Choroidal Neovascularization (CNV) VEGF-induced Retinal Leakage Ophthalmic Drug Administration Drug Administration Anterior Chamber Injection Eye drop Intravitreal Injection Retrobulbar Injection Subretinal Injection Suprachoroidal Injection Ophthalmic Examination Color / IR / Red-free Fundus Photograph Corneal Fluorescein Staining, Photographing & Scoring Direct / Indirect Ophthalmoscopy f-ERG / f-VEP / c-wave / PhNR IOP SD-OCT Slit-lamp Examination & Photographing Tear Secretion Measurement In Vitro Platform Biomarker Detection Cytokines Profiling Molecular Biology Western Blot Flow Cytometry Immuno-phenotyping Target Expression Verification TILs Analysis In Vitro Efficacy 3D Tumor Tissue Culture Cell Therapy Gene Therapy Immune Modulator In Vitro / Ex Vivo Cell Killing In Vitro Fibrosis Oncology / Immuno-oncology Platform Cell Line Derived Models Orthotopic / Metastasis CDX Models Subcutaneous CDX Models Humanized Immune Checkpoint Mouse Models Humanized Mouse Models 1st Hu CD34 Hematopoietic Stem Cell Reconstitution Mouse Model (T and B cells predominant) 2nd Hu CD34 Hematopoietic Stem Cell Reconstitution Mouse Model huPBMC Reconstitution Mouse Model Syngeneic Mouse Model Orthotopic / Metastasis Syngeneic Models Subcutaneous Syngeneic Models Inflammation & Autoimmune Diseases Platform Acute / Subacute Inflammation Cytokine Release Pharmacokinetic / Pharmacodynamic PK / PD Model (LPS / TNF-α / LPS-ATP-induced Cytokine Release Pharmacokinetic / Pharmacodynamic PK/PD Model) Ear Swelling (Xylene / Phorbol Ester-induced Ear Swelling Model) Fever (LPS / Yeast / 2,4-dinitrophenol-induced Fever Model) Granuloma (Agar / Penicillin-induced Granuloma Model) Pain Model (Acetic Acid Induced Pain Model) Plantar Swelling (Carrageenan / Zymosan-induced Plantar Swelling Model) Synovitis (LPS / MSU / Carrageenan-induced Synovitis Model) Arthritis Adjuvant Arthritis-Induced Anemia in Rats Adjuvant-induced Arthritis (AIA) Rodent Models Collagen Antibody-Induced Arthritis Model in Mice Collagen II-Induced Arthritis (CIA) in Rodents Collagen II-Induced Rheumatoid Arthritis in Non-Human Primates MSU-Induced Gouty Arthritis in Rats Autoimmune Diseases - Other Experimental Autoimmune Myasthenia Gravis (EAMG) Mouse Model Experimental Autoimmune Myocarditis (EAM) Model GVHD (Bone Marrow Transplantation-induced GVHD Model) Sjögren’s Syndrome (Salivary Gland-induced Sjögren’s Syndrome Model) Cardiovascular Diseases Acute Myocardial Infarction (Surgery-induced Acute Myocardial Infarction Model) Atherosclerosis (Diet-induced Atherosclerosis Model) Dilated Cardiomyopathy (Diet / STZ / Doxorubicin-induced Dilated Cardiomyopathy Model) Heart Failure (Surgery-induced Heart Failure Model) Hypertension (Surgery-induced Hypertension Model) Ischemia-Reperfusion Injury (Surgery-induced Ischemia-reperfusion Injury Model) Myocardial Remodeling / Hypertrophic Cardiomyopathy (Surgery-induced Myocardial Remodeling / Hypertrophic Cardiomyopathy Model) Pulmonary Arterial Hypertension (Hypoxia / Monocrotaline / SU5416-hypoxia-induced PAH Model) Right Ventricular Hypertrophy / Failure (Surgery-induced Right Ventricular Hypertrophy / Failure) Right Ventricular Infarction (Surgery-induced Right Ventricular Infarction Model) Uremic Cardiomyopathy (Surgery-induced Uremic Cardiomyopathy Model) Dermatologic Disorders Acne Vulgaris (Oleic Acid-induced Acne Model) Acrodermatitis Chronica Atrophicans (Dexamethasone-induced ACA Model) Alopecia Areata (Skin Graft-induced Alopecia Areata Model) Androgenetic Alopecia (Androgen-induced Androgenetic Alopecia Model) Atopic Dermatitis (OXA/FITC-induced Atopic Dermatitis Model) Contact Dermatitis (DNFB/OXA-induced Contact Dermatitis Model) Hand-foot Syndrome (Sorafenib-induced Hand-foot Syndrome Model) Hypertrophic scar (Surgery-induced HS Model) Itching (Histamine/Dextran-induced Itching Model) Urticaria (Anti-DNP IgE-induced Urticaria Model) Vitiligo (Monobenzone / Phenylhydroquinone / Irradiation-induecd Vitiligo Model) Diabetes and Diabetes Complications Diabetic Foot (STZ-induced Diabetic Foot Model) Diabetic Nephropathy (Diet-induced Diabetic Nephropathy Model) Diabetic Retinopathy (Diet-induced Diabetic Retinopathy Model) Type Ⅰ Diabetes (STZ-induced Type Ⅰ Diabetes Model) Type Ⅱ Diabetes (Diet-induced Type Ⅱ Diabetes Model) Dysgeusia Dysgeusia (LiCl-induced Dysgeusia Model) Eye Diseases Allergic Conjunctivitis (OVA-induced Allergic Conjunctivitis Model) Experimental Autoimmune Uveitis (IRBP-derived Peptide R16-induced Experimental Autoimmune Uveitis model) Gastrointestinal Diseases Colitis (Anti-CD40-induced Colitis Model) Colitis (DSS / DNBS / CD4+CD45RBhigh T Cells-induced Colitis Model) Diarrhea (Chemotherapy Drugs-induced Diarrhea Model) Esophageal Stricture Postoperative Adhesions (Surgery-induced Adhesion Model) Short Bowel Syndrome (Surgical Resection of Small Intestine-induced SBS Model) Gout Gout (Uric Acid Crystals-induced Gout Model) Hyperuricemia (Uric Acid Potassium Oxonate-induced Hyperuricemia Model) Hematologic Disorders Anemia in Rheumatoid Arthritis (Adjunct-induced Anemia Model in Rheumatoid Arthritis) Autoimmune Hemolytic Anemia (RBCs-induced Autoimmune Hemolytic Anemia Model) Eosinophilia (DK-PGD2-induced Eosinophilia Model) Hyponatremia (Surgery-induced Hyponatremia Model) Leukopenia (Cyclophosphamide-induced Leukopenia Model) Hepatic and Biliary Disorders Hepatic Fibrosis / Cirrhosis (CCL4 / TAA / Bile Duct Ligation-induced Hepatic Fibrosis / Cirrhosis Model) Hepatic Injury (Acetaminophen / Concanavalin A / CCL4-induced Hepatic Injury Model) Hyperlipidemia (Diet-induced Hyperlipidemia Model) Liver Failure (LPS-GalN / Antibody-induced Liver Failure Model) NASH (Diet /STZ-diet-induced NASH Model) Hypersensitivity Reaction Type Ⅲ Hypersensitivity Reaction (OVA-Adjunct-induced Arthus Reaction) Kidney Diseases Hypertensive Nephropathy (Deoxycorticosterone Acetate-induced Hypertensive Nephropathy Model) IgA Nephropathy (BSA-Adjunct / BSA-LPS-CCL4-induced IgA Nephropathy Model) Kidney Injury (Chemotherapy Drugs / Surgery / Uric Acid / Contrast Media-induced Kidney Injury Model) Membranous Nephropathy (BSA / Fx1A / B35-induced Membranous Nephropathy Model) Nephritis (Puromycin Aminonucleoside / Ureteral Ligation-induced Nephritis Model) Renal Fibrosis (Surgery-induced Renal Fibrosis Model) Lupus Cutaneous Lupus (Skin lupus) Lupus Nephritis Neuropsychiatric Lupus (NPSLE) Systemic Lupus Erythematosus (SLE) Neurological Disorders Demyelination (Cuprizone-induced Demyelination Model) Experimental Autoimmune Encephalomyelitis (MOG / PLP / MBP-induced Experimental Autoimmune Encephalomyelitis Model) Experimental Autoimmune Neuritis (SP26-induced Experimental Autoimmune Neuritis Model) Pancreatitis Psoriasis Psoriasis (IL-23-induced Psoriasis-like Model) Psoriasis (Imiquimod-induced Psoriasis-like Model) Radiation Sickness Leukopenia (Radiation-induced Leukopenia Model) Lung Injury (Radiation-induced Lung Injury Model) Salivary Gland Injury (Radiation-induced Salivary Gland Injury Model) Reproductive disorders Polycystic Ovary Syndrome (Tripterygium Glycosides-induced Polycystic Ovary Syndrome Model) Primary Ovarian Insufficiency (Cyclophosphamide-induced Primary Ovarian Insufficiency Model) Prostatic Hyperplasia (Dehydroepiandrosterone High-fat Diet-induced Prostatic Hyperplasia Model) Respiratory Diseases Asthma (OVA / HDM-induced Asthma Model) Bronchial Spasms (Bombesin-induced Bronchospasm Model) Cough (Citric Acid / Capsaicin-induced Cough Model) Dyspnea (LPS-induced Mucus Obstructs Caused Dyspnea) Eosinophilic Pneumonia (OVA-induced Eosinophilic Pneumonia Model) Idiopathic Pulmonary Fibrosis (Bleomycin Induced IPF Model) Pneumonia (Immune Complexes-induced Pneumonia Model) Pneumonia (LPA-induced Histamine Release Caused Pneumonia) Pneumonia (LPS / Poly IC-induced Pneumonia Model) Pneumonia (Papain-induced ILC2 (Innate Lymphoid Type-2 Cells) Activation Caused Pneumonia) Pulmonary Fibrosis (Citric Acid-induced Chronic Cough Caused Pulmonary Fibrosis) Rhinitis (OVA Induced Rhinitis Model) Silicosis (Crystalline Silicon Dioxide Silicosis Model) Sinusitis (OVA-Induced Sinusitis Model) Septicemia / Sepsis Sepsis (Cecal Ligation and Puncture-induced Sepsis Model) Sepsis (Fecal Extracts-induced Sepsis Model) Sepsis (LPS / D-galactosamine-induced Sepsis Model) Sepsis (LPS-induced Sepsis Model) Bone / Orthopedics Bone Loss / Osteoporosis Disuse Estrogen Deficiency Steroid Induced Bone Repair Bone Void Filler Testing in Rats, Rabbits, Mini-Pigs, Dogs & Primates Calvarial, Periodontal & Long Bone Rat Femoral Closed Fracture Spine Fusion in Rats, Rabbits & Primates Vertebral Body Bone Defects in Primates Bone Safety Adult Bone Remodeling Juvenile Bone Growth Cartilage Tissue Repair Intervertebral Disc Repair Intra-articular Particulate Injection Meniscectomy & MCL Transection Osteochondral Defect Ligament / Tendon Achilles’, ACL, Patella and Rotator Cuff Segmental Repair in Dogs and Sheep / Goats Osteoarthritis Chemically (MIA) Induced Osteoarthritis in Rats 2nd Hu CD34 Hematopoietic Stem Cell Reconstitution Mouse Model (myeloid cell line predominant) Osteomyelitis Model Pyogen-induced and Wear Debris Induced in Rats, Rabbits and Dogs Hearing Impairment Models Aminoglycoside Induced Hearing Loss Model Cisplatin Induced Hearing Loss Model Noise Induced Hearing Loss Model In Vitro Research Model Cochlea Explant Culture Ototoxicity Evaluation Auditory Brainstem Response Cochlea Paraffin Section Staining Cochlea Whole Mount Staining Distortion Product Otoacoustic Emission Histopathology Histomorphometry Bone Specialized Tissue Implant Histopathology Cancer Pathology Exakt® Histological System Inflammatory Pathology Toxicological Pathology Pain Models Nociception Test Cold Hot Plate Test Tail Flick Test Inflammatory Pain CFA Induced Chronic Allodynia Formalin Induced Pain MIA Induced Arthritic Pain Neuropathic Pain Chemotherapy Induced Peripheral Neuropathy Plantar Pain Caused by Dorsal Root Nerve Ligation SNL (Chung Model) Pain Other Postoperative Pain Visceral Pain: Acetic Acid-induced Writhing Medical Devices Active Devices Brain-Computer Interface (BCI) Endoscopy Imaging Radiofrequency Ablation Ultherapy Bone / Dental Artificial Ligament Bone Filling Materials Degradable Materials Dental REBEA Cardiovascular Devices Bolting System Degradable System DES / Balloon Heart-ear Blocker Pace System Valve Repair System Cerebrovascular Aneurysm Spoiler Device Bolting System DES (Drug-Eluting Stent) Endovascular Coiling Pipeline Others Surgical Training Apparatus Tissue Engineering Apparatus Wound Healing Apparatus Belly Patch Biodegradable Sutures Dural Graft