---
title: "Syngeneic Mouse Models"
canonical: "https://www.pharmalegacy.com/indications/oncology-immuno-oncology/syngeneic-mouse-models/"
lastmod: "2026-07-02T14:03:17+00:00"
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---

Syngeneic mouse models excel where xenograft mouse models come short. The goal of cancer immunotherapies is to promote the patient’s native anti-tumor response. Xenograft mouse models are therefore flawed in cancer immunotherapy research, given that they are devoid of a proper immune system. This is where syngeneic mouse models fill the gap: they show us how cancer immunotherapies perform with a functioning immune system.
At PharmaLegacy, we can provide you with a panel of syngeneic mouse models (22 models in total covering 14 cancer types), validated with anti-PD-1, PD-L1 and anti-CTLA-4 antibodies. Our team is hard at work to provide you with even better, newer models.
Keep checking our website for updates on the models that are still under-development, or contact us for any model development needs.