PharmaLegacy offers cutting-edge preclinical electrophysiology assessments for comprehensive sleep quality evaluation. Our tethered configured recording approach capture artifact-free, continuous polysomnography data in free moving animals concurrently with high-speed videography recordings. Our proprietary analytical pipelines deliver deep quantitative profiling of sleep architecture, including NREM/REM cycling, cataplexy arrest and arousal thresholds. These critical insights enable precise evaluation of novel drug candidates targeting neurological conditions associated with circadian rhythm such as insomnia and narcolepsy. Furthermore, our platform enables integrating electrophysiological readouts with broader range of neurological and psychiatric disorder animal models, including Alzheimer’s disease, Parkinson’s disease and depression. Beyond validated disease models, we offer custom protocol design and algorithm implementation with regulatory-ready, high integrity datasets designed to accelerate