Non-Human Primates Capabilities

Hematology / Thrombosis Models

  • Arteriovenous Bypass (AV-shunt) Thrombosis Model
  • Balloon Injury-Induced Arterial Thrombosis
  • Bleeding Time Test in Rat Tail or Rabbit Ear / Nail or Arm-skin of Cynos
  • Collagen / FⅧ Induced Hemophilia
  • FeCl3 Induced Thrombosis Model
  • Heart Failure Model
  • Hemorrhagic Stroke Model
  • Immune Thrombocytopenia (ITP) Model Induced by an Anti-GPIIb/IIIa Antibody
  • IVC Stenosis Model of Venous Thrombosis
  • Middle Cerebral Artery Occlusion (MCAO) Induced Stroke Model
  • Myocardial Infarction
  • Myocardial Ischemia / Reperfusion Injury in Rat
  • Venous Bypass Thrombosis Model (V-shunt)

In Vitro Testing Services

  • Blood Cell Culture Stimulation Experiment In Vitro
  • Coagulation Measurement
  • In Vitro Determination of Dose-effect of Anticoagulants
  • In Vitro Measurement of Platelet Aggregation

Inflammation / Immune Disease Models

  • Acute Hepatitis Induced by Acetaminophen
  • Asthma-like Th2 Response Induced by Multiple A.Suum Challenges in Monkey
  • B-cell Depletion Therapy
  • Balloon Synovitis of the Back
  • Bile Duct Ligation Induced Hepatic Fibrosis
  • Bleomycin-induced Pulmonary Fibrosis
  • Chemotherapy Induced Mucositis Model
  • Collagen II-induced Rheumatoid Arthritis (RA) Model
  • Dextran Sulfate Sodium (DSS)-induced Colitis Model
  • Endometriosis Model Induced by Ectopic Implantation
  • Escherichia Coli Induced Skin Blister
  • I.V Low Dose of Lipopolysaccharide (LPS)-induced Cytokines Production Model
  • Induced Atopic Dermatitis
  • Inflammatory Anemia Model
  • Intrabronchial LPS-induced Acute Lung Injury (ALI) Model
  • Keyhole Limpet Hemocyanin (KLH)-induced T cell Dependent Antibody Response (TDAR) Model
  • LPS-induced Systemic Inflammation Model
  • MOG Induced EAE
  • Tetanus Toxoid (TTx)-induced Delayed Type Hypersensitivity (DTH) Model

Metabolic Diseases Models

  • Animal Model of Hyperuricemia
  • Gastric Peristalsis Model
  • Functional Dyspepsia
  • Hyperlipidemia Model
  • Intravenous Glucose Tolerance Test (IVGTT) / Oral Glucose Tolerance Test (OGTT) Model

Ophthalmology Models

  • Antibody Drug Conjugate (ADC) Induced Corneal Toxicity
  • Efficiency and Efficacy Evaluation of Ocular Gene Therapy
  • Laser-induced Choroidal Neovascularization (CNV) Model

Other NHP Models & Studies

  • Blood Cell Apheresis
  • Cutaneous Wound Healing and Scarring
  • Plantar Pain Caused by Dorsal Root Nerve Ligation

PK, PD-Tox

  • Anti-Drug Antibody Test (ADA)
  • Non-GLP Toxicology Experiment
  • Pharmacokinetic Analysis Test
  • PK-APTT Steady-state Dose Exploration Test


  • Bioanalysis for Large Molecules (Proteins, Antibodies, ADC, Peptides, ADA)
  • Bioanalysis for Small Molecules

Candidate Screening / IND Package

In Vitro Absorption, Distribution, Metabolism & Excretion

  • Metabolism Identification (Liver Microsomes / Hepatocytes / S9 / In Vivo)
  • Metabolite Stability (Liver Microsomes / Hepatocytes / Plasma)
  • P450 Enzyme (Inhibition / Phenotyping / Induction / TDI)
  • Permeability (Caco-2, MDCK-MDR1-II / PUMPA)
  • Plasma Protein Binding
  • Red Blood Cell / Plasma Partition Ratio

Pharmacokinetic (PK) Studies in Rodents, Rabbits, Canines, Pigs & Non-Human Primates

  • Bioavailability & Bioequivalence
  • Blood Brain Barrier
  • Drug Distribution in Tissues
  • Mass Balance (Excretion of Feces, Urine & Bile)
  • PK Profile & PK Parameters

Toxicology (Non-GLP) in Rodents, Rabbits, Canines, Pigs & Non-Human Primates

  • Clinical Pathology / Histopathology
  • Repeat Dose Toxicology (DRF, NOAEL)
  • Single Dose Toxicology (MTD, LD50)
  • Topical Toxicity & Systemic Toxicity
  • Toxicokinetics
Ophthalmic Diseases Models


  • Cataract Model in Rats


  • CA-I Induced Retinal Edema
  • Oxygen-Induced Retinopathy (OIR)
  • STZ Induced Diabetic Retinopathy


  • Blue Light / Bright Light-induced Retinopathy
  • MNU-induced Retinal Degeneration
  • Oxidative Stress Induced Geographic Atrophy
  • Sodium Iodate Induced RPE / Retinal Degeneration

Gene Therapy

  • CAG-LSL-ZsGreen Mice
  • Colony Management and Phenotyping
  • Functional Assessment


  • Acute Intraocular Hypertension
  • Chronic Intraocular Hypertension
  • NMDA Induced RGC Damage
  • Optic Nerve Clamping-induced RGC Damage

Ocular Inflammation

  • Allergic Conjunctivitis
  • Conjunctivitis Induced by Staphylococcal Infection
  • Graves’ Orbitopathy
  • IRBP-induced EAU in Mouse / Rat
  • LPS-induced EIU
  • OVA-induced EAC

Ocular Surface Disease

  • Benzalkonium Induced Corneal Epithelial Damage
  • Corneal Neovascularization Induced by Stitching / NaOH Burn (Rabbit)
  • Ocular Pain Test
  • Scopolamine + Low Humidity Induced Dry Eye (Mouse)

Other Retinal Diseases

  • Inherited Retinal Disease Models
  • Proliferative Vitreoretinopathy (PVR) in Rabbits
  • Retinal Vein Occlusion (RVO) in Rats
  • Two-Stage Laser-induced Subretinal Fibrosis


  • Myopia
  • Presbyopia


  • Choroid Sprouting Assay
  • DL-AAA-induced Retinal Neovascularization and Leakage
  • HUVEC Tube Formation Assay
  • Laser-induced Choroidal Neovascularization (CNV)
  • VEGF-induced Retinal Leakage
Ophthalmic Drug Administration

Drug Administration

  • Anterior Chamber Injection
  • Eye drop
  • Intravitreal Injection
  • Retrobulbar Injection
  • Subretinal Injection
  • Suprachoroidal Injection
Ophthalmic Examination

Ophthalmic Examination

  • Color / IR / Red-free Fundus Photograph
  • Corneal Fluorescein Staining, Photographing & Scoring
  • Direct / Indirect Ophthalmoscopy
  • f-ERG / f-VEP / c-wave / PhNR
  • IOP
  • SD-OCT
  • Slit-lamp Examination & Photographing
  • Tear Secretion Measurement
In Vitro Platform

Biomarker Detection

  • Cytokines Profiling
  • Molecular Biology
  • Western Blot

Flow Cytometry

  • Immuno-phenotyping
  • Target Expression Verification
  • TILs Analysis

In Vitro Efficacy

  • 3D Tumor Tissue Culture
  • Cell Therapy
  • Gene Therapy
  • Immune Modulator
  • In Vitro / Ex Vivo Cell Killing
  • In Vitro Fibrosis
Oncology / Immuno-oncology Platform

Cell Line Derived Models

  • Orthotopic / Metastasis CDX Models
  • Subcutaneous CDX Models

Humanized Immune Checkpoint Mouse Models

Humanized Mouse Models

  • 1st Hu CD34 Hematopoietic Stem Cell Reconstitution Mouse Model (T and B cells predominant)
  • 2nd Hu CD34 Hematopoietic Stem Cell Reconstitution Mouse Model
  • huPBMC Reconstitution Mouse Model

Syngeneic Mouse Model

  • Orthotopic / Metastasis Syngeneic Models
  • Subcutaneous Syngeneic Models
Inflammation & Autoimmune Diseases Platform

Acute / Subacute Inflammation

  • Cytokine Release Pharmacokinetic / Pharmacodynamic PK / PD Model (LPS / TNF-α / LPS-ATP-induced Cytokine Release Pharmacokinetic / Pharmacodynamic PK/PD Model)
  • Ear Swelling (Xylene / Phorbol Ester-induced Ear Swelling Model)
  • Fever (LPS / Yeast / 2,4-dinitrophenol-induced Fever Model)
  • Granuloma (Agar / Penicillin-induced Granuloma Model)
  • Pain Model (Acetic Acid Induced Pain Model)
  • Plantar Swelling (Carrageenan / Zymosan-induced Plantar Swelling Model)
  • Synovitis (LPS / MSU / Carrageenan-induced Synovitis Model)


  • Adjuvant Arthritis-Induced Anemia in Rats
  • Adjuvant-induced Arthritis (AIA) Rodent Models
  • Collagen Antibody-Induced Arthritis Model in Mice
  • Collagen II-Induced Arthritis (CIA) in Rodents
  • Collagen II-Induced Rheumatoid Arthritis in Non-Human Primates
  • MSU-Induced Gouty Arthritis in Rats

Autoimmune Diseases - Other

  • Experimental Autoimmune Myasthenia Gravis (EAMG) Mouse Model
  • Experimental Autoimmune Myocarditis (EAM) Model
  • GVHD (Bone Marrow Transplantation-induced GVHD Model)
  • Sjögren’s Syndrome (Salivary Gland-induced Sjögren’s Syndrome Model)

Cardiovascular Diseases

  • Acute Myocardial Infarction (Surgery-induced Acute Myocardial Infarction Model)
  • Atherosclerosis (Diet-induced Atherosclerosis Model)
  • Dilated Cardiomyopathy (Diet / STZ / Doxorubicin-induced Dilated Cardiomyopathy Model)
  • Heart Failure (Surgery-induced Heart Failure Model)
  • Hypertension (Surgery-induced Hypertension Model)
  • Ischemia-Reperfusion Injury (Surgery-induced Ischemia-reperfusion Injury Model)
  • Myocardial Remodeling / Hypertrophic Cardiomyopathy (Surgery-induced Myocardial Remodeling / Hypertrophic Cardiomyopathy Model)
  • Pulmonary Arterial Hypertension (Hypoxia / Monocrotaline / SU5416-hypoxia-induced PAH Model)
  • Right Ventricular Hypertrophy / Failure (Surgery-induced Right Ventricular Hypertrophy / Failure)
  • Right Ventricular Infarction (Surgery-induced Right Ventricular Infarction Model)
  • Uremic Cardiomyopathy (Surgery-induced Uremic Cardiomyopathy Model)

Dermatologic Disorders

  • Acne Vulgaris (Oleic Acid-induced Acne Model)
  • Acrodermatitis Chronica Atrophicans (Dexamethasone-induced ACA Model)
  • Alopecia Areata (Skin Graft-induced Alopecia Areata Model)
  • Androgenetic Alopecia (Androgen-induced Androgenetic Alopecia Model)
  • Atopic Dermatitis (OXA/FITC-induced Atopic Dermatitis Model)
  • Contact Dermatitis (DNFB/OXA-induced Contact Dermatitis Model)
  • Hand-foot Syndrome (Sorafenib-induced Hand-foot Syndrome Model)
  • Hypertrophic scar (Surgery-induced HS Model)
  • Itching (Histamine/Dextran-induced Itching Model)
  • Urticaria (Anti-DNP IgE-induced Urticaria Model)
  • Vitiligo (Monobenzone / Phenylhydroquinone / Irradiation-induecd Vitiligo Model)

Diabetes and Diabetes Complications

  • Diabetic Foot (STZ-induced Diabetic Foot Model)
  • Diabetic Nephropathy (Diet-induced Diabetic Nephropathy Model)
  • Diabetic Retinopathy (Diet-induced Diabetic Retinopathy Model)
  • Type Ⅰ Diabetes (STZ-induced Type Ⅰ Diabetes Model)
  • Type Ⅱ Diabetes (Diet-induced Type Ⅱ Diabetes Model)


  • Dysgeusia (LiCl-induced Dysgeusia Model)

Eye Diseases

  • Allergic Conjunctivitis (OVA-induced Allergic Conjunctivitis Model)
  • Experimental Autoimmune Uveitis (IRBP-derived Peptide R16-induced Experimental Autoimmune Uveitis model)

Gastrointestinal Diseases

  • Colitis (Anti-CD40-induced Colitis Model)
  • Colitis (DSS / DNBS / CD4+CD45RBhigh T Cells-induced Colitis Model)
  • Diarrhea (Chemotherapy Drugs-induced Diarrhea Model)
  • Esophageal Stricture
  • Postoperative Adhesions (Surgery-induced Adhesion Model)
  • Short Bowel Syndrome (Surgical Resection of Small Intestine-induced SBS Model)


  • Gout (Uric Acid Crystals-induced Gout Model)
  • Hyperuricemia (Uric Acid Potassium Oxonate-induced Hyperuricemia Model)

Hematologic Disorders

  • Anemia in Rheumatoid Arthritis (Adjunct-induced Anemia Model in Rheumatoid Arthritis)
  • Autoimmune Hemolytic Anemia (RBCs-induced Autoimmune Hemolytic Anemia Model)
  • Eosinophilia (DK-PGD2-induced Eosinophilia Model)
  • Hyponatremia (Surgery-induced Hyponatremia Model)
  • Leukopenia (Cyclophosphamide-induced Leukopenia Model)

Hepatic and Biliary Disorders

  • Hepatic Fibrosis / Cirrhosis (CCL4 / TAA / Bile Duct Ligation-induced Hepatic Fibrosis / Cirrhosis Model)
  • Hepatic Injury (Acetaminophen / Concanavalin A / CCL4-induced Hepatic Injury Model)
  • Hyperlipidemia (Diet-induced Hyperlipidemia Model)
  • Liver Failure (LPS-GalN / Antibody-induced Liver Failure Model)
  • NASH (Diet /STZ-diet-induced NASH Model)

Hypersensitivity Reaction

  • Type Ⅲ Hypersensitivity Reaction (OVA-Adjunct-induced Arthus Reaction)

Kidney Diseases

  • Hypertensive Nephropathy (Deoxycorticosterone Acetate-induced Hypertensive Nephropathy Model)
  • IgA Nephropathy (BSA-Adjunct / BSA-LPS-CCL4-induced IgA Nephropathy Model)
  • Kidney Injury (Chemotherapy Drugs / Surgery / Uric Acid / Contrast Media-induced Kidney Injury Model)
  • Membranous Nephropathy (BSA / Fx1A / B35-induced Membranous Nephropathy Model)
  • Nephritis (Puromycin Aminonucleoside / Ureteral Ligation-induced Nephritis Model)
  • Renal Fibrosis (Surgery-induced Renal Fibrosis Model)


  • Cutaneous Lupus (Skin lupus)
  • Lupus Nephritis
  • Neuropsychiatric Lupus (NPSLE)
  • Systemic Lupus Erythematosus (SLE)

Neurological Disorders

  • Demyelination (Cuprizone-induced Demyelination Model)
  • Experimental Autoimmune Encephalomyelitis (MOG / PLP / MBP-induced Experimental Autoimmune Encephalomyelitis Model)
  • Experimental Autoimmune Neuritis (SP26-induced Experimental Autoimmune Neuritis Model)


  • Pancreatitis


  • Psoriasis (IL-23-induced Psoriasis-like Model)
  • Psoriasis (Imiquimod-induced Psoriasis-like Model)

Radiation Sickness

  • Leukopenia (Radiation-induced Leukopenia Model)
  • Lung Injury (Radiation-induced Lung Injury Model)
  • Salivary Gland Injury (Radiation-induced Salivary Gland Injury Model)

Reproductive disorders

  • Polycystic Ovary Syndrome (Tripterygium Glycosides-induced Polycystic Ovary Syndrome Model)
  • Primary Ovarian Insufficiency (Cyclophosphamide-induced Primary Ovarian Insufficiency Model)
  • Prostatic Hyperplasia (Dehydroepiandrosterone High-fat Diet-induced Prostatic Hyperplasia Model)

Respiratory Diseases

  • Asthma (OVA / HDM-induced Asthma Model)
  • Bronchial Spasms (Bombesin-induced Bronchospasm Model)
  • Cough (Citric Acid / Capsaicin-induced Cough Model)
  • Dyspnea (LPS-induced Mucus Obstructs Caused Dyspnea)
  • Eosinophilic Pneumonia (OVA-induced Eosinophilic Pneumonia Model)
  • Idiopathic Pulmonary Fibrosis (Bleomycin Induced IPF Model)
  • Pneumonia (Immune Complexes-induced Pneumonia Model)
  • Pneumonia (LPA-induced Histamine Release Caused Pneumonia)
  • Pneumonia (LPS / Poly IC-induced Pneumonia Model)
  • Pneumonia (Papain-induced ILC2 (Innate Lymphoid Type-2 Cells) Activation Caused Pneumonia)
  • Pulmonary Fibrosis (Citric Acid-induced Chronic Cough Caused Pulmonary Fibrosis)
  • Rhinitis (OVA Induced Rhinitis Model)
  • Silicosis (Crystalline Silicon Dioxide Silicosis Model)
  • Sinusitis (OVA-Induced Sinusitis Model)

Septicemia / Sepsis

  • Sepsis (Cecal Ligation and Puncture-induced Sepsis Model)
  • Sepsis (Fecal Extracts-induced Sepsis Model)
  • Sepsis (LPS / D-galactosamine-induced Sepsis Model)
  • Sepsis (LPS-induced Sepsis Model)
Bone / Orthopedics

Bone Loss / Osteoporosis

  • Disuse
  • Estrogen Deficiency
  • Steroid Induced

Bone Repair

  • Bone Void Filler Testing in Rats, Rabbits, Mini-Pigs, Dogs & Primates
  • Calvarial, Periodontal & Long Bone
  • Rat Femoral Closed Fracture
  • Spine Fusion in Rats, Rabbits & Primates
  • Vertebral Body Bone Defects in Primates

Bone Safety

  • Adult Bone Remodeling
  • Juvenile Bone Growth

Cartilage Tissue Repair

  • Intervertebral Disc Repair
  • Intra-articular Particulate Injection
  • Meniscectomy & MCL Transection
  • Osteochondral Defect

Ligament / Tendon

  • Achilles’, ACL, Patella and Rotator Cuff Segmental Repair in Dogs and Sheep / Goats


  • Chemically (MIA) Induced Osteoarthritis in Rats
  • 2nd Hu CD34 Hematopoietic Stem Cell Reconstitution Mouse Model (myeloid cell line predominant)

Osteomyelitis Model

  • Pyogen-induced and Wear Debris Induced in Rats, Rabbits and Dogs
Hearing Impairment Models

Hearing Impairment Models

  • Aminoglycoside Induced Hearing Loss Model
  • Cisplatin Induced Hearing Loss Model
  • Noise Induced Hearing Loss Model

In Vitro Research Model

  • Cochlea Explant Culture

Ototoxicity Evaluation

  • Auditory Brainstem Response
  • Cochlea Paraffin Section Staining
  • Cochlea Whole Mount Staining
  • Distortion Product Otoacoustic Emission


  • Bone
  • Specialized Tissue Implant


  • Cancer Pathology
  • Exakt® Histological System
  • Inflammatory Pathology
  • Toxicological Pathology
Pain Models

Nociception Test

  • Cold Hot Plate Test
  • Tail Flick Test

Inflammatory Pain

  • CFA Induced Chronic Allodynia
  • Formalin Induced Pain
  • MIA Induced Arthritic Pain

Neuropathic Pain

  • Chemotherapy Induced Peripheral Neuropathy
  • Plantar Pain Caused by Dorsal Root Nerve Ligation
  • SNL (Chung Model) Pain


  • Postoperative Pain
  • Visceral Pain: Acetic Acid-induced Writhing
Medical Devices

Active Devices

  • Brain-Computer Interface (BCI)
  • Endoscopy
  • Imaging
  • Radiofrequency Ablation
  • Ultherapy

Bone / Dental

  • Artificial Ligament
  • Bone Filling Materials
  • Degradable Materials
  • Dental

Cardiovascular Devices

  • Bolting System
  • Degradable System
  • DES / Balloon
  • Heart-ear Blocker
  • Pace System
  • Valve Repair System


  • Aneurysm Spoiler Device
  • Bolting System
  • DES (Drug-Eluting Stent)
  • Endovascular Coiling
  • Pipeline


Surgical Training Apparatus

Tissue Engineering Apparatus

Wound Healing Apparatus

  • Belly Patch
  • Biodegradable Sutures
  • Dural Graft