In vitro tests in NHPs offer a clear advantage when compared to in vitro tests in other animal models: their close physiologic and anatomic resemblance to humans allow them to be used in studies requiring high degrees of homology. For instance, the toxicity of monoclonal antibodies is mainly driven by their pharmacological activity, hence prior safety studies before clinical testing needs to be done in species in which the mAb binds and interacts with targets to a similar extent to that anticipated in humans.
The solution? In vitro NHP models.
Available at PharmaLegacy? Without a doubt.
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MODELS / SERVICES
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- Electronically managed, traceable research data
- PK/PD, molecular pharmacology and preliminary toxicology adjacency studies
- 24/7 access to PharmaLegacy representatives
- Capacity to house over 30,000 rodents and large animals
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