Acute renal injury and failure can be caused by many types of insults, ranging from an acute ischemic injury, severe blood loss, and sepsis. This has created a significant challenge when trying to create proper preclinical models that cover all of them, given their very different pathophysiology. At PharmaLegacy, we provide our clients with a number of different preclinical acute kidney disease models, including Ischaemia-reperfusion (I/R) in rats/hamster rats, Cisplatin induced kidney injury in hamster rats and adenine induced kidney injury in mice. More models means a more complete understanding of your treatments’ effects on the disease state, and ultimately a more advanced understanding of human nephropathy.

Can’t find what you’re looking for in our available models? Not a concern – we’re experts at model development and would gladly create the precise model you need for your studies.. Get in touch with one of our experts now and let’s discuss things further.