Reproducible heart failure models for your pipelines.

The most challenging aspect of designing a translatable and reproducible animal model of heart failure is assuring certain characteristics, namely rapid ventricular pacing, repetitive transmyocardial direct current shock, chronic heart block supraventricular stenosis, arteriovenous shunt, and increased peripheral resistance.

At PharmaLegacy, our heart failure models, including myocardial infarction, myocardial ischemic reperfusion and pressure overload hypertrophy, are precision-crafted to ensure they faithfully emulate the human disease state, thereby providing your studies with the reproducibility and translatability your pipeline needs.

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Heart Failure


Case Study: Rat Model of Myocardial Infarction (MI)

A clinically predictive model for acute or chronic heart failure is used to test resembling changes in physiopathology and histopathology in the development of heart failure post MI in humans, and to predict responses to pharmacologic interventions.

Clinical Parameters

Echocardiograph (M mode)

Reactive Fibrosis

Committed to quality:

  • 24/7 access to PharmaLegacy representatives
  • AAALAC and CNAS guidelines-adherent animal studies
  • Research data electronically managed by BioBook (IDBS, UK)
  • Clients have real-time remote monitoring of studies

If you are looking for comprehensive preclinical development services, you are at the right place. Get in touch with our team of highly trained professionals and let’s get your pipeline moving.

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