PK Studies
Unwavering quality in PK studies
Animal PK studies are valuable tools for screening compounds during the candidate optimization stage of drug discovery. PK studies provide valuable information on compounds including exposure, AUC, clearance, and half-life, etc. Proper PK studies can help speed up discovery, and ensure only compounds with desirable PK profiles are advanced into the clinic.
At PharmaLegacy, we perform whole ranges of animal PKs with species ranging from rodents to non-human primates (NHPs). We have more than a decade of experience servicing clients worldwide. Our vivarium is AAALAC accredited.
MODELS / SERVICES
WT Mouse: CD-1, C57BL/6, BALB/c, Nude Mouse
Transgenic Mouse
Rat: SD, Wistar Han
Guinea Pig
Hamster
Case Study: Large Molecule PK in Mouse
Case Study: Cassette Dosing PK in Mouse
Dog: Beagle
Monkey: Cynomolgus
Rabbit: New Zealand
Minipig: Bama
Case Study: Large Molecule PK in Monkey
Single Dose
Repeat Dose
Intravenous (Bolus and Infusion)
Oral (Solution, Suspension, Tablet, Capsule)
Subcutaneous
Intramuscular
Intraarticular
Intraperitoneal
Transdermal
Rectal
Intrathecal
5 working days for single period studies for 90% of studies.
AUC, Half-life, Clearance, etc.
PK Calculation with WinNonlin
Extensively validated preclinical models:
- Completed over 400 FDA / CFDA IND filings
- Scientific staff with an average of over 15 years of experience in pharmacology
- PK/PD, molecular pharmacology and preliminary toxicology adjacency studies
- Capacity to house over 30,000 rodents and large animals
Work with the CRO that has the most experience in pharmacology. Work with PharmaLegacy.
DMPK studies demand flexibility. Can yours meet their goals?
When it comes to DMPK, flexibility is paramount. The right assay and instrumentation are all critical to ensuring you can meet your study goals and obtain meaningful, clinically relevant data.
Download our DMPK brochure and see how PharmaLegacy is equipped to ensure you get the answers you need, no matter how challenging the study.
We’re ready when you are.
Tell us your pharmacology challenges.
