Rigorous multifactorial autoimmune disease models.

Systemic Lupus Erythematosus (SLE) is characterized by the excessive production of autoantibodies and their deposition in a variety of organs (namely the kidneys and skin). Being an idiopathic multisystem autoimmune disease, SLE’s etiology is considered to be multifactorial and is still poorly understood.

Finding cures and treatments for multifactorial autoimmune disease like SLE is a task that demands excellence in the tiniest of details, from data collection all the way to proper model selection. A task our team of experts at PharmaLegacy has been trained for years to handle. Keep scrolling to get more information on our SLE in MRL/Ipr and NZB/W F1 mice and our Pristane induced SLE in wild and humanized mice models.

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Systemic Lupus Erythematosus


Case Study:

SLE Model in NZB/W F1 Mice

SLE Model in MRL/MpJ-Faslpr Mice

Animals: Female MRL/MpJ-Faslpr mice and MRL/MpJ mice, 7 weeks old

Model: Spontaneous

End Points: Blood Urea Nitrogen (BUN) biochemistry kit; Anti-dsDNA IgG ELISA kit

The capability to succeed:

  • Capacity to house over 30,000 rodents and large animals
  • 1000+ validated animal models of disease spanning 40+ diseases
  • 380,000 square feet of facility space
  • 24/7 access to PharmaLegacy representatives

Seeking uncompromising quality with deep skills and knowledge? Contact PharmaLegacy.

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Can you trust your animal model to provide you with the correct answers?

No animal study can predict with complete certainty how a therapy will perform in human subjects, but it is PharmaLegacy’s job to ensure that you come as close to certainty as possible. Download our brochure on non-human primate (NHP) models and see how PharmaLegacy ensures that y our studies utilize the most physiologically relevant models.

    Immune NHP Models Brochure

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