BaF3 Assays
Obtaining clarity on cellular mechanisms
The BaF3 cell proliferation assay offers a valuable platform for deciphering intricate mechanisms governing cellular growth and proliferation. This robust tool leverages the unique characteristics of the interleukin-3-dependent murine pro-B cell line to address multifaceted questions spanning the realms of kinase inhibitor potency, oncogenic transformation, resistance prediction, signal transduction pathways, and off-target screening.
Whether you are trying to determine the potency of kinase inhibitors, running rescue experiments for off-target screening using IL-3, or assessing the small-molecule kinase inhibitors resistance elicited by point mutations, you need to be allied to an experienced and robust CRO. PharmaLegacy can be this ally. Let us tell you why. At PharmaLegacy, we boast:
- More than 350 BaF3 engineering cell lines
- Multiple target WT and mutant cell lines
- Coverage of most kinase families
- Multiple readouts available (CTG, CCK8, MTT, LDH, and more)
- Customized cell line generation available
Don’t waste any time:
MODELS / SERVICES
Committed to quality:
- FDA part 11 compliant
- Animal studies strictly follow AAALAC and ILAC guidelines
- Electronically managed, traceable research data
- Rigorous adherence to international GLP and QA best practices
- Clients have real-time remote monitoring of studies
Want your scientific discoveries to become treatments? PharmaLegacy’s the right partner for you.
Providing Better Data For Critical Oncology Pipeline Decisions
To advance a compound from discovery to clinical, or to halt its development, is a huge and costly decision. For the benefit of you and your company, and for the well-being of patients in need of treatment, that decision needs to be based on correct information.
Download our Integrated In Vitro Oncology Assays brochure and see why over 300 pharmaceutical companies, including many global leaders, trust PharmaLegacy for the unbiased, accurate information they need to make critical oncology pipeline decisions.
We’re ready when you are.
Tell us your pharmacology challenges.