General inflammation models for your critical inflammation studies.

Tumor, rubor, calor, and dolor. These terms were coined by the Roman encyclopedist Celsus in the 1st century A.D to describe the four classical signs of inflammation. 20 centuries later, we are still trying to better understand how inflammation works, but more importantly, how the inflammatory process goes awry, and how to stop it from doing so.

Keep scrolling through our website to check out all our available inflammation models: looking for a chronic inflammation model? Have a look at our Cotton-Induced Granuloma model in rats. Looking for an acute inflammation model? Check out our Carrageenan-induced Paw Edema.

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General Inflammation


Case Study: Carrageenan-induced Paw Edema in Wistar Rats

Aim: Establish carrageenan-induced paw edema model in the wistar rats and examine the effect of indomethacin and dexamethasone.

Animal: Wistar rats

Reagent: Carrageenan: Sigma

Effect of Indo/Dex on Paw Edema

LPS-induced Cytokine Production in Mouse Plasma

Aim: Examine the effect of prednisone on LPS-induced TNF-α production in mice.

Animal: BALB/c mice

Reagent: LPS

Mouse TNF-α kit: R&D System

Effect of Prednisone on LPS-induced TNF-α Production

Carrageenan-induced Acute Inflammation in The Mouse Air Pouch Model

Aim: Examine the effect of dexamethasone on carrageenan-induced acute inflammation in the mouse air pouch mode.

Animal: C57BL/6, mice, male, 6-8 weeks.

Reagent: Carrageenan: Sigma

Effects of Dexamethasone on Cell Migration

Effects of Dexamethasone on Exudate Volume

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