On the Role of Humanized Mouse Models in Immuno-oncology Research

October 14, 2022 /

If you’ve been keeping up with the latest advancements in cancer research, you might come across the usage of humanized mouse models as a promising tool in cancer management and treatment. This trend is driven by advances in the development of new rodent models which enabled scientists to further investigate and harness the power of immunotherapies in fighting tumors by replacing the mouse’s immune system with a functioning human one, hence the term “humanized”. But first, what is a humanized mouse model? A humanized mouse model is established by modifying specific genes that render it immunodeficient, lacking T, B, and [...]