Preclinical Cardiovascular CRO

Only 12.8% of drugs which enter phase 1 clinical trials ever receive marketing approval. Why is that? Preclinical data said one thing, then the clinical data was different. At PharmaLegacy, our goal is to get you the most confident answer as early as possible so you can make the right decisions for your cardiovascular pipeline.

Start Your Cardiovascular Study Now

There are a number of things a preclinical cardiovascular CRO can do to reduce your clinical attrition rates:

  • Use models which most faithfully represent the human disease state
  • Design the studies to ensure they generate data with the appropriate statistical power to answer the question at hand confidently
  • Assign experienced laboratory personnel, ensuring they adhere to detailed SOPs, to minimize human error
  • Maintain objectivity and honesty in research and reporting. The only bad information is incorrect information.

This is what PharmaLegacy delivers.

Your data can’t be any better than your models or the people who run your studies. PharmaLegacy has been developing models for decades, rigorously validating each one. Our scientists average 15 years of professional scientific experience and 5 years with PharmaLegacy.  There is a good reason why 12 of the top 20 pharmaceutical companies trust PharmaLegacy. You can expect more when you choose PharmaLegacy as your cardiovascular CRO.

Humanized Mouse Models Humanized Mouse Models

Start Your Cardiovascular Study Immediately!

Contact PharmaLegacy today.

Our Cardiovascular Models & Services Include:

  • Uremic Cardiomyopathy (Surgery-induced Uremic Cardiomyopathy Model)
More Info on Cardiorenal Syndrome Models
  • Acute Myocardial Infarction (Surgery-induced Acute Myocardial Infarction Model)
  • Heart Failure (Surgery or Biochemical Drug-induced Heart Failure Model)
  • Myocardial Ischemia-Reperfusion Injury (Surgery-induced Myocardial Ischemia-Reperfusion Model)
  • Myocardial Remodeling / Hypertrophic Cardiomyopathy (Surgery or Biochemical drug-induced Myocardial Remodeling / Hypertrophic Cardiomyopathy Model, Transgenic Mice Model)
  • Dilated Cardiomyopathy (Drug-induced Dilated Cardiomyopathy Model, Transgenic Mice Model)
  • Right Ventricular Hypertrophy / Failure (Surgery-induced Right Ventricular Hypertrophy / Failure)
  • Right Ventricular Infarction (Surgery-induced Right Ventricular Infarction Model)
  • Myocarditis (Experimental Autoimmune Myocarditis Model)
More Info on Heart Disease Models
  • Anemia in Rheumatoid Arthritis (Adjunct-induced Anemia Model in Rheumatoid Arthritis)
  • Antibody / Antigen-induced Immune Thrombocytopenia (ITP) Model
  • Autoimmune Hemolytic Anemia (RBCs-induced Autoimmune Hemolytic Anemia Model)
  • Eosinophilia (DK-PGD2-induced Eosinophilia Model)
  • Hemophilia A Model
  • Collagen / FⅧ Induced Hemophilia
  • Hyponatremia (Surgery-induced Hyponatremia Model)
  • Leukopenia (Cyclophosphamide-induced Leukopenia Model)
  • Intracerebral Hemorrhage Model
  • Ischemia-Reperfusion Stroke, Middle Cerebral Artery Occlusion (MCAO)-induced
More Info on Stroke Models
  • Arteriovenous Bypass (AV-shunt) Thrombosis Model
  • Balloon Injury-Induced Arterial Thrombosis
  • FeCl3-Induced Thrombosis Model
  • Immune Thrombocytopenia (ITP) Model Induced by an Anti-GPIIb/IIIa Antibody
  • IVC Stenosis Model of Venous Thrombosis
  • Venous Bypass Thrombosis Model (V-shunt)
More Info on Thrombosis Models
  • Atherosclerosis (Diet-induced Atherosclerosis Model, Transgenic Mice Model)
  • Tissue Ischemia-Reperfusion Injury (Surgery-induced Tissue Ischemia-Reperfusion Injury Model)
  • Pulmonary Arterial Hypertension (Hypoxia / Monocrotaline / SU5416-hypoxia-induced PAH Model)
  • Hypertension (Spontaneous Hypertension Model, Surgery or Drug-induced Model)
  • Bolting System
  • Degradable System
  • DES / Balloon
  • Heart-ear Blocker
  • Pace System
  • Valve Repair System
  • and more!
More Info on Cardiovascular Device Testing
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Let PharmaLegacy provide the answers you need.

    Comprehensive Pharmacology Capabilities for Demanding Cardiovascular Studies

    No study will predict with certainty how a therapy will perform in human subjects, but with over 1500 validated models, including non-human primate models, choosing PharmaLegacy as your preclinical cardiovascular CRO will ensure your study comes as close as possible.

    Need more? Ask us about customized model development. We are developing new models continually, and would gladly develop one for your study. Model development doesn’t need to be a big deal: you’ll be surprised how cost-effective and time-efficient model development with PharmaLegacy can be.

    Preclinical Testing for Cardiovascular Medical Devices

    PharmaLegacy has decades of experience with medical device testing. Not only will our models help provide better data, but our team understands the requirements to obtain FDA IDE (and equivalent approval from the EMA and other regulatory bodies) for significant risk devices and can help design your studies to ensure you get the data necessary for any regulatory submissions. Choose PharmaLegacy as your CRO for preclinical medical device testing and let’s swiftly and efficiently get you the data you need to advance your investigational device towards clinical testing.

    START YOUR CARDIOVASCULAR STUDY TODAY

      Time is valuable. Why wait months to start your cardiovascular study? Our advertised models are maintained in stock and we can start most studies in under two weeks!

      With an extensive catalog of over 1500 readily available models, scientific staff averaging over 15 years of experience, and surprisingly affordable pricing, PharmaLegacy has been the preclinical CRO of choice for many global life science leaders. See what over 300 global pharmaceutical, biotech, and medical device companies have realized: when you choose PharmaLegacy as your cardiovascular CRO, you can expect more.